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New Study Reveals We Have One Thing to Thank Gonorrhea For_我的网站

A |     Researchers from the University of California's San Diego School of Medicine have found that gonorrhea, as unpleasant as it is, might be the reason that our grandparents even exist.,Humans are among the few species that continue to live after menopause, which might be because of the evolution-proven support that older women provide when it comes to raising children.,The new findings suggest that pressure from pathogens like gonorrhea developed human gene mutations that protected elderly people from cognitive decline and made sure they could live longer.,The discovery comes by comparing human and chimpanzee genomes. The comparison revealed that humans have their own unique version of the gene for CD33, a receptor in immune cells that plays an important role in binding to a type of sugar called sialic acid. Human cells are coated with it and it helps immune cells "recognize" other cells and not attack them.,"Somewhere along the evolutionary line, humans picked up an additional mutated form of CD33 that is missing the sugar-binding site," the authors said. "The mutated receptor no longer reacts to sialic acids on damaged cells and plaques, allowing the microglia to break them down. Indeed, higher levels of this CD33 variant were independently found to be protective against late-onset Alzheimer's.",It would seem that CD33 was selected by evolution for its survival advantages, later making sure that humans were able to have big families that represent several generations. All of this, albeit indirectly, thanks to gonorrhea.。    与2021年的更新一样，12.9英寸的iPad Pro采用了Mini LED显示技术，以提高黑色水平、更好的对比度和HDR性能，而较小的型号则坚持实用配置较低的屏幕，但两者都支持苹果的ProMotion功能，刷新率最高可达120Hz。新款iPad Pro保持了苹果公司自2018年以来一直使用的整体设计，当时该公司首次取消了Home键，以最大限度地扩大显示面积。但很难说这是一面"全面屏"，因为四面仍有明显的边框，持续四年的外观设计依然持续至今。新款iPad Pro有一个新的 "悬停"Apple Pencil功能，当触控笔稍稍位于屏幕上方时，系统就会检测到它。苹果公司表示，这让用户 "在做标记之前看到他们的预览"。这也让用户能够以更高的精度进行素描和插图，并使用户用Apple Pencil做的一切事情更加轻松。

B | 例如，使用Scribble时，当铅笔靠近屏幕时，文本字段会自动展开，手写的内容会更快地转换为文本。

C | 第三方应用程序也可以利用这项新功能，实现全新的标记和绘画体验。苹果公司表示，iPadOS 16是该平台最新的主要软件更新，将在本月某个时候发布。iPadOS落后于iOS 16发布的部分原因是苹果在一个名为"Stage Manager"的新功能上的挣扎，它被描述为"轻松完成多任务的新方法"，在测试期间，一些iPad高级用户对其反应不佳，并被批评为性能有问题。苹果已经对Stage Manager的一些反馈做出了回应，推迟了对外部显示器的支持，并扩大了该功能支持更多iPad型号的范围。M2 iPad Pro支持目前最快的Wi-Fi 6E，下载速度最高可达2.4Gb/s，比上一代产品快2倍。而Wi-Fi+蜂窝型号同时还支持5G（sub-6GHz和mmWave）。新的11英寸和12.9英寸iPad Pro将有银色和太空灰外观，配置为128GB、256GB、512GB、1TB和2TB。11英寸的iPad Pro起价为799美元，现在就可以订购。M2 iPad Pro将于10月26日星期三上市。

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